Douglas Gould Laboratory

Developing mechanism-based interventions for diseases of the extracellular matrix

Welcome to the Gould Lab!

Our broad mission is to understand the biological functions of a specialized extracellular matrix structure called the Basement Membrane.

Our primary focus is a multi-system disorder that is caused by mutations in the genes encoding type IV collagen alpha 1 (COL4A1) and COL4A2.

Our goal is to understand the tissue-specific molecular mechanisms that underlie this syndrome and develop mechanism-based therapies that can prevent, reduce or delay disease in patients.

Step inside to learn more about what we are doing and the people that are making it all happen!


Employment Opportunities

The Gould Lab routinely accepts volunteers, graduate students, medical student, residents and postdoctoral fellows. If you are a highly motivated, ambitious, and creative researcher, please send your CV along with a cover letter and the contact information for two or three references.